Exciting Discovery Published in Science
FastStep™ kinetic analysis helps identify growth factor progranulin's role in preventing arthritis by blocking TNF binding to its receptor.
The Growth Factor Progranulin Binds to TNF Receptors and Is Therapeutic Against Inflammatory Arthritis in Mice, Wei Tang, Yi Lu, Qing-Yun Tian, Yan Zhang, Feng-Jin Guo, Guang-Yi Liu, Nabeel Muzaffar Syed, Yongjie Lai, Edward Alan Lin, Li Kong, Jeffrey Su, Fangfang Yin, Ai-Hao Ding, Alexandra Zanin-Zhorov, Michael L. Dustin, Jian Tao, Joseph Craft, Zhinan Yin, Jian Q. Feng, Steven B. Abramson, Xiu-Ping Yu, Chuan-ju Liu, Science (2011), doi 10.1126/science.1199214